intrasaccular technology advantage
Intrasaccular Solution
3D Coverage / Versatility
3D Coverage / Versatility
Intrasaccular device that provides a 3D endo-skeleton enabling a stable adjunctive scaffold for coil embolization. With no intraluminal presence, Syntra does not require dual antiplatelet therapy (DAPT).
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3D Coverage / Versatility
3D Coverage / Versatility
3D Coverage / Versatility
Syntra can be used in a wide range of aneurysm scenarios such as wide neck sidewall, bifurcation, ruptured, and unruptured, monolithic implant design conformable to adjust to irregular morphologies. Available in Syntra-21 & Syntra-17 delivery profile platforms.
Wide Neck Reduction
3D Coverage / Versatility
Wide Neck Reduction
"Secure the Neck"
Provides a stable endo-bridge scaffold to effectively reduce the neck of the aneurysm.
Tortuous Access
Sizing / Selection
Sizing / Selection
Capable in navigating tortuous vasculature with acute angulations that presents challenging scenarios for the user/operator (i.e. Ophthalmic ICA sidewall & bifurcation aneurysm's).
Sizing / Selection
Sizing / Selection
Sizing / Selection
Similar sizing & measurement methodology comparative to standard 3D "Framing" coils (i.e. aneurysm width, height, depth & neck diameter via angiography).
Ease of Use
Sizing / Selection
Familiar Workflow
Syntra in conjunction with coils can use a single microcatheter to treat typical cerebral aneurysms. The device is delivered with an integrated mechanical detachment system with no external accessories.
Familiar Workflow
Sizing / Selection
Familiar Workflow
Syntra follows a standard bare platinum coiling workflow, using fewer coils, fewer devices, and fewer steps—resulting in reduced radiation exposure, less contrast media, and lower overall patient risk during complex aneurysm treatments.
Syntra Technology
Integrated Mechanical Detachment System
Syntra provides an integrated mechanical detachment system compatible Ø0.021”& Ø0.017” microcatheter. It is actuated by removing the lock, then mechanically translating the slider (i.e. Syringe-like actuation) proximally to detach & release the implant. No external detachment handle accessory required.
Syntra Origami Technology
Syntra is an intrasaccular "Origami" implant that delivers through a microcatheter and unfolds in linear segments within the aneurysmal sac (in-situ) to form a stable 3D scaffold endoskeleton structure to reconstruct/reduce the aneurysm's wide neck.
2025 PILOT STUDY (safety & efficacy) achievement
Primary Performance Attributes
- Ability to navigate/negotiate acute angulated wide neck cerebral aneurysms (WNSA/WNBA/Irregular)
- Offers 3D endoskeleton lattice structural neck & dome scaffold support for ruptured & unruptured intracranial aneurysm scenarios
- Implant sizing similar to standard coil embolization procedures
- Syntra Intrasaccular "Stent" offers superior wide neck endo-bridge protection
- "Ease-of-Use" conditions similar to coiling
- Enables less coils per aneurysm embolization procedure
- No changes to current cath-lab "Work-Flow" for treating IA's
- Single-microcatheter treatment solution
- No DAPT (100% Intrasaccular)
Syntra Pilot Study Case Overview (2025)
SYNTRA TREATMENT STRATEGY
- Ophthalmic ICA "Irregular" aneurysm (6mo. DSA)
- Dimensions: W=14.6, H=6.9, L=6.9, N=4.6 (mm)
- Syntra SKU: DS-7 (7.0mm dia.)
- Acute angulated Wide Neck Sidewall Aneurysm (WNSA)
- Zoned irregular aneurysm treatment
- Neck reduction/coverage (Zone-2 Syntra 7mm)
- Utilize large volumetric XL-type filling coils (≥ 30cm)
- Coil embolization (Zones-1/2/3)
- Coil packing density >26% achieved
- Complete aneurysm obliteration at 6mo. DSA follow up
Syntra Pilot Study Case Overview (2025)
SYNTRA TREATMENT STRATEGY
- Ophthalmic ICA aneurysm (6mo. DSA)
- Acute angulated Wide Neck Sidewall Aneurysm (WNSA)
- Dimensions: W=8.8 H=7.4, L=7.4, N=5.0 (mm)
- Syntra SKU: DS-7 (7.0mm dia.)
- Utilize large volumetric XL-type filling coils (≥ 30cm)
- Coil packing density >28.1% achieved
- Complete aneurysm obliteration at 6mo. DSA follow up
Syntra-21 & Syntra-17 Platform
- Syntra-21: compatible with 0.021" ID single microcatheter - use platform in clinical phase (13-SKU's)
- Syntra-17: compatible with 0.0165" - 0.017" ID single microcatheter - use platform in development phase (up to 13-SKU's)
- Available from 4mm - 10mm (0.5mm incremental SKU sizes)
- Capable of treating aneurysms up to 11mm+ diameters